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Recombinant Mouse CCL22

CAT: 0171-Z200315Size: 20 µgDry Ice: NoHazardous: No
CAT#:0171-Z200315Size:20 µg
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Description
CCL22 was described initially as a constitutively produced, thymus-specific chemokine, implicated in the recruitment of T cells. One of the functions of CCL22 originally described was induction of migration of CCR4+ Th2 cells, but it has additionally been shown to regulate migration of Tregs. CCL22 has been implicated in a number of diseases, including allergen-induced lung inflammation, atopic dermatitis, and lymphoma. Similarly, a presumed role for CCR4+ cells has been suggested for endotoxic shock, rheumatoid arthritis, T cell lymphoma, and autoimmune diabetes
CAS Number
9000-83-3
Gene Name
CCL22
Gene Aliases
C-C motif chemokine 22, Activated B and dendritic cell-derived, CC chemokine ABCD-1, Small-inducible cytokine A22, Abcd1, Scya22
Recombinant Mouse Macrophage-Derived Chemokine (CCL22)
Gene ID
20299
Accession Number
O88430
Organism
Mouse
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by its ability to chemoattract human T cells using a concentration range of 10-50 ng/mL.
Molecular Weight
8
Shipping Conditions
Ambient Temperature
Storage Conditions
Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant mouse CCL22 is presented as 0.2 μm filtered PBS pH 7.5.

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