Products for Research Use Only
RegisterLogin

Recombinant Mouse Beta-Defensin 2 (DEFB2)

CAT: 0171-Z200289Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0171-Z200289Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Defensins are a large family of peptides of which two groups exist in mammals: alpha defensins and beta defensins - which are distinguishable by the spacing and connectivity of the conserved cysteine residues within the mature peptides. It is thought that the function of defensins in the eradication of pathogens from the host system is to insert themselves into the bacterial membrane under the influence of membrane potential, in doing so forming channels which lead to leakage of cytoplasmic molecules and cell death. Unlike hBD-1, this second peptide, human beta-defensin-2 (hBD-2), is regulated at a transcriptional level in response to contact with microorganisms, and is highly effective in killing the gram negative bacteria Its expression is also upregulated by the cytokine tumor necrosis factor-alpha.
CAS Number
9000-83-3
Gene Name
DEFB2
Gene Aliases
BD-2, mBD-2, Defensin, beta 2, Defb2
Gene ID
13215
Accession Number
P82020
Organism
Mouse
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED(50) was Determined by its ability to chemoattract immature human dendritic cells using a concentration range of 1-50 ng/mL.
Molecular Weight
6
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant Mouse beta Defensin-2 was lyophilized from 0.2 μm filtered 100 mM NaCl, 20 mM PB, pH 7.4.

Related Products

CatalogName
Z200279Recombinant Mouse Beta-Defensin 3 (DEFB3)
Z200275Recombinant Mouse Beta-Defensin 3 (DEFB3)
Z200269Recombinant Mouse Beta-Defensin 1 (DEFB1)
Z200265Recombinant Mouse Beta-Defensin 1 (DEFB1)
Z100025Recombinant Human Beta-Defensin 1 (DEFB1)
Z100027Recombinant Human Beta-Defensin 1 (DEFB1)
Z100029Recombinant Human Beta-Defensin 1 (DEFB1)
Z100037Recombinant Human Beta-Defensin 2 (DEFB4A)
Z100039Recombinant Human Beta-Defensin 2 (DEFB4A)
Z100035Recombinant Human Beta-Defensin 2 (DEFB4A)

Alternative Products

CatalogName
MBS4159944-01Recombinant Mouse Beta-Defensin 2 (DEFB2)
RPU41159-01Recombinant Mouse Defensin Beta 2 (DEFb2)
154322-01Defensin Beta 2 (DEFb2) Recombinant, Mouse
TRV-039781-01Recombinant Defensin Beta 2 (DEFb2)
MBS1105836-01Recombinant Mouse Beta-defensin 2 (Defb2), partial
R0377mMouse Defb2 / Beta-defensin 2 Recombinant Protein
499807Beta-Defensin 2, Recombinant, Mouse (DEFB2, BD-2, mBD-2, Defensin, Beta 2, Defb2) discontinued
154323-01Defensin Beta 2 (DEFb2) Recombinant, Rat
RPU41160-01Recombinant Rat Defensin Beta 2 (DEFb2)
MBS1031863-01Recombinant Bovine Beta-defensin 2 (DEFB2)

Popular Products