Products for Research Use Only
RegisterLogin

Recombinant Human WNT1

CAT: 0171-Z102125Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0171-Z102125Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Wnt-1 is a secreted protein that signals through the frizzled family of seven transmembrane receptors. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the up-regulation of over fifty genes. Stabilization and resulting accumulation of the intracellular signaling protein β-catenin is an important aspect of Wnt-1 signaling. While known to play in role as a developmental protein, elevated levels of Wnt proteins have also been associated with tumorigenesis.
CAS Number
9000-83-3
Gene Name
WNT1
Gene Aliases
Proto-oncogene Int-1 homolog, Wnt-1
Recombinant Human Proto-oncogene Wnt-1 (WNT1)
Gene ID
7471
Accession Number
P04628
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (0.1% BSA) and store in working aliquots at -20 to -80⁰C
Function
Determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells. The expected ED50 for this effect is 1.5 - 2.5 ng/ml in the presence of 200ng/ml of human BMP-2.
Molecular Weight
38.5
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in Tris and DTT

Related Products

CatalogName
50443051WNT1 Adenovirus (Human)
50443171WNT1 siRNA Oligos set (Human)
50443101WNT1 AAV Vector (Human) (CMV)
50443011WNT1 ORF Vector (Human) (pORF)
ORF035927WNT1 ORF Vector (Human) (pORF)
50443054Wnt1 Adenovirus (Mouse)
50443055WNT1 Adenovirus (Mouse)
50443056WNT1 Adenovirus (Rat)
K2641501WNT1 sgRNA CRISPR Lentivector set (Human)
50443021WNT1 Protein Vector (Human) (pPM-C-HA)

Alternative Products

CatalogName
MBS4159824-01Recombinant Human WNT1
PPT-16056Human WNT1 Recombinant Protein
TP762591WNT1 (NM_005430) Human Recombinant Protein
GTR19137559-01Recombinant Human WNT1 Protein, N-His
MBS951613-01Recombinant Human Proto-oncogene Wnt-1 (WNT1)
rAP-0817WNT1 Inducible Signaling Pathway Protein 2 Human Recombinant
R1414hHuman WNT1 / Proto-oncogene Wnt-1 Recombinant Protein
MBS141334-01Recombinant Human WNT1 Inducible Signaling Pathway Protein 1
MBS9020256-01Recombinant Human Proto-oncogene Wnt-1 (WNT1), partial
MBS146742-01Recombinant Human WNT1 Inducible Signaling Pathway Protein 2

Popular Products