Recombinant Human VEGFB

• Description:

  Vascular endothelial growth factor B (VEGFB) is a homodimeric, heparin-binding glycoprotein member of the VEGF family of growth factors. Compared to VEGFA, VEGFB’s main role is the maintenance of newly formed blood vessels and is involved in endothelial cell physiology. It is a ligand for vascular endothelial growth factor receptor 1 (VEGFR1) and neuropilin-1 (NRP1), while the binding of neuropilin-1 to VEGFB186 is proteolysis regulated.

• Gene Name:

  VEGFB

• Gene Aliases:

  VEGF-related factor

• Gene ID:

  7423

• Accession Number:

  P49765

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method

• Purity:

  >95% as determined by SDS-PAGE

• Function:

  Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is < 1ng/ml.

• Molecular Weight:

  19

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage, we recommend adding a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized as a 0.2 µm filtered solution in Acetonitrile and TFA

• CAS Number:

  9000-83-3