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Recombinant Human TRAIL (TNFSF10)

CAT: 0171-Z101755Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0171-Z101755Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A cytotoxic protein, TRAIL initiates apoptosis in tumor cells by binding the death-signalling receptors; DR4 and DR5. In its active conformation, TRAIL forms homotrimers. TRAIL transcripts have been shown to be constitutively expressed in a variety of human tissues. There are five known TRAIL receptors: two which transduce apoptotic signals, two which function as decoys to block TRAIL-induced apoptosis and osteoptotegrin.
CAS Number
9000-83-3
Gene Name
TNFSF10
Gene Aliases
TRAIL, Tumor necrosis factor (Ligand) family member 10, TNFSF10, Apo2 Ligand, TL2
Recombinant Human TNF-Related Apoptosis-Inducing Ligand (TNFSF10)
Gene ID
8743
Accession Number
P50591
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 20 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin
Function
N.A.
Molecular Weight
19.5
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

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