Recombinant Human TGFA

• Description :

  An EGF family member, TGF-A is a cytokine that is produced following the protease digestion of its trans-membrane precursor proTGF-A. TGF-A is expressed both in normal tissues during embryogenesis and in adult tissues, such as the brain, keratinocytes, and macrophages and at high levels in transformed and tumour cells.

• Gene Name :

  TGFA

• Gene Aliases :

  TGF-alpha, TGF-A, isoform CRA_d
  Recombinant Human Transforming Growth Factor Alpha (TGFA)

• Gene ID :

  7039

• Accession Number :

  P01135

• Organism :

  Human

• Source :

  E. coli

• Concentration :

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity :

  >95% as determined by SDS-PAGE

• Solubility :

  Reconstitute at 100 μg/mL in sterile 10 mM Acetic Acid

• Function :

  Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED(50) for this effect is typically 0.1­0.4 ng/mL.

• Molecular Weight :

  5.8

• Shipping Conditions :

  Ambient Temperature

• Storage Conditions :

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance :

  Lyophilized Powder

• Formulation :

  Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA

• CAS Number :

  9000-83-3