Recombinant Human TFF3

• Description:

  Found in the gastrointestinal tract, the three Trefoil proteins, TFF1, 2, and 3 have been shown to play an important role in intestinal mucosal defence and repair. In addition to being expressed by goblet cells and in the uterus, TFF3 has also been shown to express in certain cancers providing a potential use as a molecular marker for those cancers.

• Gene Name:

  TFF3

• Gene Aliases:

  Intestinal trefoil factor, ITF, Polypeptide P1.B, hP1.B
  Recombinant Human Trefoil Factor 3 (TFF3)

• Gene ID:

  7033

• Accession Number:

  Q07654

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  Reconstitute at 100 μg/mL in sterile PBS

• Function:

  The ED(50) was determined by the dose-dependent proliferation of KTC cells and was found to be <0.5ng/mL.

• Molecular Weight:

  6.8

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS

• CAS Number:

  9000-83-3