Recombinant Human TFF2

• Description:

  Found in the gastrointestinal tract, the three Trefoil proteins, TFF1, 2, and 3 have been shown to play an important role in intestinal mucosal defence and repair. Specifically, TFF2 has been shown to inhibit gastrointestinal motility and secretion of the gastric acid.

• Gene Name:

  TFF2

• Gene Aliases:

  TFF2, Spasmolysin, Spasmolytic polypeptide, SP
  Recombinant Human Trefoil Factor 2 (TFF2)

• Gene ID:

  7032

• Accession Number:

  Q03403

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  Reconstitute at 100 μg/mL in sterile PBS

• Function:

  The ED(50) was determined by the dose-dependent proliferation of immortalized human pancreatic cells and was found to be <5ng/mL.

• Molecular Weight:

  12.3

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS

• CAS Number:

  9000-83-3