Products for Research Use Only
RegisterLogin

Recombinant Human RANTES (CCL5)

CAT: 0171-Z100789Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0171-Z100789Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RANTES belongs to the family of chemotactic cytokines known as chemokines. RANTES is expressed by an early response gene. The synthesis of RANTES is induced by TNF-alpha and IL-1-alpha. RANTES is chemotactic for T cells, human eosinophils and basophils and plays an active role in recruiting leukocytes into inflammatory sites. RANTES also activates eosinophils to release, for example, eosinophilic cationic protein. It changes the density of eosinophils and makes them hypodense, which is thought to represent a state of generalized cell activation and is associated most often with diseases such as asthma and allergic rhinitis. RANTES also is a potent activator of oxidative metabolism specific for eosinophils. RANTES increases the adherence of monocytes to endothelial cells. It selectively supports the migration of monocytes and T lymphocytes expressing the cell surface markers CD4 and UCHL1. These cells are thought to be pre-stimulated T helper cells with memory T cell functions. RANTES activates human basophils from some select basophil donors and causes the release of histamines.
CAS Number
9000-83-3
Gene Name
CCL5
Gene Aliases
Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, Small-inducible cytokine A5, T cell-specific protein P228, TCP228, T-cell-specific protein RANTES, D17S136E, SCYA5
Gene ID
6352
Accession Number
P13501
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by its ability to chemoattract human blood monocytes using a concentration range of 1-10 ng/mL.
Molecular Weight
8
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant Rantes/CCL5 was lyophilized from a 0.2 μm filtered PBS solution.

Related Products

CatalogName
15374051CCL5 Adenovirus (Human)
Y123163Anti-Rantes
15374101CCL5 AAV Vector (Human) (CMV)
ORF002046CCL5 ORF Vector (Human) (pORF)
15374171CCL5 siRNA Oligos set (Human)
15374011CCL5 ORF Vector (Human) (pORF)
15374056CCL5 Adenovirus (Rat)
15374054CCL5 Adenovirus (Mouse)
K0389201CCL5 sgRNA CRISPR Lentivector set (Human)
K0389204CCL5 sgRNA CRISPR Lentivector (Human) (Target 3)

Alternative Products

CatalogName
PT_41931-01Rantes Human Recombinant (CCL5) (Rantes Human)
278-RN-010Recombinant Human CCL5/RANTES
7-02082Recombinant Human Rantes (CCL5)
OPSD00133-5UGRecombinant RANTES / CCL5
22060469-1Human Rantes (CCL5), (Recombinant)
90232-BHuman RANTES (CCL5) Recombinant
MBS553007-01Human RANTES-CCL5 Recombinant
rAP-0252Rantes Human Recombinant (CCL5)
R1100-22RANTES, Recombinant, Human (CCL5)
P6596-5μgRecombinant Human RANTES/CCL5

Popular Products