Recombinant Human Prolactin (PRL)

• Description:

  Synthesized primarily by the pituitary gland, prolactin is a neuroendocrine hormone that functions to promote and maintain lactation and has also been shown to play a role in breast cancer development, regulation of reproductive function and immune-regulation. While Human prolactin shares only 60% and 63% amino acid sequence identity with mouse and rat prolactin, respectively, the human prolactin receptor can be activated by Rat PRL. abm's Recombinant Human PRL is a single, non-glycosylated polypeptide chain with a molecular mass of 23 KDa.

• Gene Name:

  PRL

• Gene Aliases:

  Luterotropic hormone, Lutetropin, Mammotropin, PRL

• Gene ID:

  5617

• Accession Number:

  P01236

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  It is recommended to reconstitute lyophilized PRL in sterile distilled water to no less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.

• Molecular Weight:

  23

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a concentrated (1mg/ml) solution in PBS.

• CAS Number:

  9000-83-3