Products for Research Use Only
RegisterLogin

Recombinant Human PDGFB

CAT: 0171-Z100357Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0171-Z100357Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The PDGF family is comprised of five different disulphide-linked dimers of four different polypeptide chains: A, B, C and D (PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD). Synthesized mainly by megakaryocytes, PDGFs are stored in the alpha granules of platelets from which they are released following platelet activation. Functioning as an autocrine and paracrine growth factor, PDGFs are involved in a number of biological processes that include but not limited to hyperplasia, chemotaxis, embryonic neuron development, wound healing and respiratory tubule epithelial cell development. Aberrant expression of PDGFs is observed with vascular proliferative diseases such as atherosclerosis. PDGFs regulate the synthesis of their own receptor and also influence the expression of membrane receptors for IL1, EGF, 5-Hydroxytryptamine, LDL and transferrin. Recombinant human PDGFB is a disulfide-linked homodimer of two B chains.
CAS Number
9000-83-3
Gene Name
PDGFB
Gene Aliases
PDGF subunit B, PDGF-2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis, PDGF-BB
Recombinant Human Platelet-Derived Growth Factor Subunit B (PDGFB)
Gene ID
5155
Accession Number
P01127
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED50 as determined by the dose-dependent proliferation of NIH 3T3 cells is <0.5ng/ml
Molecular Weight
12.3
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS

Related Products

CatalogName
36302051PDGFB Adenovirus (Human)
36302011PDGFB ORF Vector (Human) (pORF)
ORF007632PDGFB ORF Vector (Human) (pORF)
36302101PDGFB AAV Vector (Human) (CMV)
36302171PDGFB siRNA Oligos set (Human)
LV568pLenti-SFFV-PDGFB
LV520pLenti-PGK-PDGFB
36302054PDGFB Adenovirus (Mouse)
36302056PDGFB Adenovirus (Rat)
K1620201PDGFB sgRNA CRISPR Lentivector set (Human)

Alternative Products

CatalogName
RPF11045-01Recombinant Human PDGFB
PX-P3029-50Human PDGFB Recombinant Protein
CRP2078-01Recombinant Human PDGFB Protein
bs-47344P-01Recombinant human PDGFB Protein (HEK293)
MBS1572822-01Recombinant Human PDGFB, N-His
TMPY-04644-01PDGFB Protein, Human, Recombinant (His)
YHB91201Recombinant Human PDGFB Protein, N-His
KMH584-01Recombinant Human PDGFB Protein, His Tag
GTR19065205-01Recombinant Bovine PDGFB protein (PDGFB), Partial
E55A12426Human PDGFB

Popular Products