Recombinant Human OPG (TNFRSF11B)

• Description:

  A member of the TNF superfamily, OPG is expressed in many different tissues, including the heart, liver, lung and bone marrow although it main role is to mediate bone density. When expressed, the protein may form dimers or stay in its monomeric form. The three dimensional structure of OPG can be divided into seven distinct domains, four of which correspond to the extracellular region of TNFR proteins and constitutes the soluble form of OPG.

• CAS Number:

  9000-83-3

• Gene Name:

  TNFRSF11B

• Gene Aliases:

  OCIF, Tumor necrosis factor receptor superfamily member 11B, TNFRSF11B, Osteoprotegerin, TNFRSF11B, TR1
  Recombinant Human Osteoclastogenesis Inhibitory Factor (TNFRSF11B)

• Gene ID:

  4982

• Accession Number:

  O00300

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  N.A.

• Molecular Weight:

  20

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.2