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Recombinant Human NRG4

CAT: 0171-Z100905Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0171-Z100905Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.
CAS Number
9000-83-3
Gene Name
NRG4
Gene Aliases
Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG4
Recombinant Human Neuregulin-4 (NRG4)
Gene ID
145957
Accession Number
Q8WWG1
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED(50) was determined by the dose-dependent proliferation of Raji cells and was found to be <0.05ng/mL.
Molecular Weight
7
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered PBS, pH 7.4 solution.

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