Recombinant Human MMP2

• Description:

  MMP-2 belongs to a family of endoproteases which need calcium and zinc in order to exert their catalytic capability (extracellular matrix remodeling). The elevated expression of these enzymes has been linked to many degenerative disorders, such as arthritis, cancer metastasis and skeletal growth-plate disorders. It has been shown that MMP-2 associates with many connective tissue cells as well as neutrophils, macrophages and monocytes.

• Gene Name:

  MMP2

• Gene Aliases:

  MMP-2, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, TBE-1
  Recombinant Human Matrix Metalloproteinase-2 (MMP2)

• Gene ID:

  4313

• Accession Number:

  P08253

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  < 1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  N.A.

• Molecular Weight:

  62

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Supplied as a 0.2 μm filtered solution in Tris, CaCl2, NaCl and Brij­35

• CAS Number:

  9000-83-3