Recombinant Human MIP-1 beta (CCL4L1)

• Description:

  MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5.

• Gene Name:

  CCL4L1

• Gene Aliases:

  C-C motif chemokine 4-like, G-26, T-lymphocyte-secreted protein HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP1B, SCYA4
  Recombinant Human Lymphocyte Activation Gene-1 (CCL4L1)

• Gene ID:

  388372

• Accession Number:

  Q8NHW4

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  Determined by its ability to chemoattract human blood monocytes using a concentration range of 2-10 ng/mL.

• Molecular Weight:

  8.1

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered PBS solution

• CAS Number:

  9000-83-3