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Recombinant Human MIG (CXCL9)

CAT: 0171-Z100669Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z100669Size:1 mg
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Description
MIG (CXCL9) protein belongs to the family of chemotactic cytokines known as chemokines. The synthesis of MIG is specifically induced in macrophages and in other cells by IFN-gamma.Human neutrophils produce mig in response to IFN-gamma in combination with either TNF-alpha or bacterial lipopolysaccharides and this response is blocked by IL-10 and IL-4. MIG is a chemoattractant for stimulated but not resting T cells, however it is not active on neutrophils or monocytes.
CAS Number
9000-83-3
Gene Name
CXCL9
Gene Aliases
C-X-C motif chemokine 9, Gamma-interferon-induced monokine, Monokine induced by interferon-gamma, Small-inducible cytokine B9, CMK, HuMIG, SCYB9, CXCL9
Gene ID
4283
Accession Number
Q07325
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by its ability to chemoattract human peripheral blood T lymphocytes using a concentration range of 10-80 ng/mL.
Molecular Weight
11
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant MIG/CXCL9 was lyophilized from 1.0 mg/mL solution in 25 mM NaCl 10 mM PB pH 7.0.

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