Products for Research Use Only
RegisterLogin

Recombinant Human LIF

CAT: 0171-Z100605Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0171-Z100605Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LIF is a multifunctional secreted glycoprotein that exists in both soluble and matrix bound forms. It displays biologic activities ranging from the differentiation of myeloid leukemic cells into macrophage lineage to effects on bone metabolism, inflammation, neural development, embryogenesis, and the maintenance of implantation. It is now clear that LIF is related in both structure and mechanism of action to the interleukin IL-6 family of cytokines, which also includes IL-11, ciliary neurotrophic factor, oncostatin M, and cardiotrophin 1. The actions of these cytokines are mediated through specific cell-surface receptors that consist of a unique chain and the shared signal transducing subunit gp130.
CAS Number
9000-83-3
Gene Name
LIF
Gene Aliases
LIF, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI)
Recombinant Human Leukemia Inhibitory Factor (LIF)
Gene ID
3976
Accession Number
P15018
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED50 was in found to be <0.2 ng/ml as determined by the dose-dependent proliferation of human erythroleukemic cell line.
Molecular Weight
20
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered PBS pH 7.0

Related Products

CatalogName
Z400019Recombinant Porcine LIF
Z200485Recombinant Mouse LIF
Z400017Recombinant Porcine LIF
Z200199Recombinant Mouse LIF
Z200195Recombinant Mouse LIF
Z200197Recombinant Mouse LIF
Z400015Recombinant Porcine LIF
26514051LIF Adenovirus (Human)
26514011LIF ORF Vector (Human) (pORF)
26514101LIF AAV Vector (Human) (CMV)

Alternative Products

CatalogName
ARP2794-01Recombinant Human Leptin Human Recombinant Protein
MBS7612987-01Recombinant Human WAS
P0015Recombinant Human AND
CC014-010Recombinant Human Apoliprotein-J (Clusterin Human Recombinant)
054-85TWEAK, recombinant / TNFSF12, recombinant (Human)
PT_39973-01Beta 2 Microglobulin Human Recombinant (B2M Human Recombinant)
PT_40053-01C-Reactive Protein Human Recombinant (CRP Human Recombinant)
P10106-01Recombinant Human FSH alpha+Recombinant Human FSH beta
P1294-.005Recombinant Human Epiregulin
P1136-.01Recombinant Human TSLP

Popular Products