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Recombinant Human Leptin (LEP)

CAT: 0171-Z101857Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z101857Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Leptin is a cytokine found in the adipose tissue of animals (Leptin mRNA is restricted to the adipose tissue). Leptin has been shown to suppress appetite, increase thermogenesis and reduce body weight, food consumption and plasma glucose levels.
CAS Number
9000-83-3
Gene Name
LEP
Gene Aliases
OB, Obese protein, Obesity factor
Gene ID
3952
Accession Number
P41159
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 1 mg/mL in sterile 20 mM Tris-­HCI (pH 8.0).
Function
The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.5ng/mL.
Molecular Weight
16.4
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl.

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