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Recombinant Human IL7

CAT: 0171-Z100977Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Z100977Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL7 is a secreted cytokine of the hemopoietin family that primarily affects early B and T cells and plays an important role in stimulating the proliferation of lymphoid progenitors. IL7 is produced by stromal epithelial cells of the thymus, bone marrow, and intestines. Human and murine IL7 share 60% sequence homology at the primary level and known to exhibit cross species activity. Designated CD127, the human IL7 receptor is a strongly glycosylated membrane protein of 76 kDa. Recombinant Human IL7 is a 17.7 kDa, non-glycosylated protein.
CAS Number
9000-83-3
Gene Name
IL7
Gene Aliases
IL-7
Recombinant Human Interleukin-7 (IL7)
Gene ID
3574
Accession Number
P13232
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED50 as determined by dose-dependent stimulation of mouse lymphoma was <0.5ng/ml
Molecular Weight
17.7
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in sodium phosphate and NaCl

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