Recombinant Human IL36A

• Description:

  IL-1 epsilon is an actively secreted member of the IL-1 family of cytokines. It is mainly expressed in tissues with epithelial cells and in psoriatic plaques, as well as by monocytes, B cells and T cells. IL-1 epsilon has been shown to signal through the IL-Rrp2 receptor which is primarily expressed on certain denditic cells, and to act as an agonist of NF-kappaB which then stimulates the inflammatory response in bronchial epithelial cells.

• Gene Name:

  IL36A

• Gene Aliases:

  IL-1 Epsilon, FIL1 epsilon, Interleukin-1 family member 6, IL-1F6, IL-36 gamma, IL-1F, IL-1H1
  Recombinant Human Interleukin-36 alpha (IL36A)

• Gene ID:

  27179

• Accession Number:

  Q9UHA7

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin

• Function:

  N.A.

• Molecular Weight:

  17.4

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS, NaCl and Tween® 20 with BSA as a carrier protein

• CAS Number:

  9000-83-3