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Recombinant Human IL28B (IFNL3)

CAT: 0171-Z101285Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0171-Z101285Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
CAS Number
9000-83-3
Gene Name
IFNL3
Gene Aliases
IL-28B, Interferon lambda-3, IFN-lambda-3, Cytokine Zcyto22, Interleukin-28C, IL-28C, ZCYTO22
Recombinant Human Interleukin-28B (IFNL3)
Gene ID
282617
Accession Number
Q8IZI9
Organism
Human
Source
CHO cells
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The activity was determined by a WISH cell viral resistance assay with a linear range of 4-20 ng/mL.
Molecular Weight
23
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant Human Interleukin-28B was lyophilized from a 0.2 μm filtered PBS solution pH 7.4.

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