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Recombinant Human IL17D

CAT: 0171-Z102425Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0171-Z102425Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells.
CAS Number
9000-83-3
Gene Name
IL17D
Gene Aliases
Interleukin-27
Gene ID
53342
Accession Number
Q8TAD2
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute in sterile 4mM HCl at 100µg/mL (containing at least 0.1% human or bovine serum albumin)
Function
The ED50 is 7.5-37.5 ng/mL as determined by its binding ability in a functional ELISA (at a concentration of 1 µg/mL)
Molecular Weight
20.5
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein)

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