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Recombinant Human GMFB

CAT: 0171-Z101119Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z101119Size:1 mg
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Description
GMF-beta is a 17-kDa brain-specific protein that was isolated from bovine brain homogenate as a substance inducing the maturation of normal neurons as well as glial cells, and at first, it was considered to be a neurotrophic factor. The amino acid sequence of GMFB is highly conserved among many species, suggesting that it plays basic roles across many species. The expression of GMF-b is largely limited to the brain, especially the glial cells and some neurons. Schwann cells of the distal segment of the transected nerve express GMF-b, and this induction of GMF-b coincides with the temporal expression of nerve growth factor receptors in the cell.
CAS Number
9000-83-3
Gene Name
GMFB
Gene Aliases
GMF-beta, GMFB
Recombinant Human Glia Maturation Factor Beta (GMFB)
Gene ID
2764
Accession Number
P60983
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
ED50 not determined.
Molecular Weight
15
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant GMFB was lyophilized from a 0.2 μm filtered 20 mM PB,130 mM NaCl solution pH 7.5.

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