Recombinant Human GDF3

• Description :

  GDF-3 is a growth and differentiation factor which belongs to the TGF-beta superfamily. GDF-3 and GDF-9 are the only two members of the family which do not form disulfide-linked dimers. GDF-3 has been found in adult bone marrow, spleen, thymus, and adipose tissue. Although signaling in all other members of the family involve the BMP receptors ALK1,2,3, and 6, GDF-3 signals through BMP receptors ALK4 and 7.

• Gene Name :

  GDF3

• Gene Aliases :

  GDF-3
  Recombinant Human Growth Differentiation Factor 3 (GDF3)

• Gene ID :

  9573

• Accession Number :

  Q9NR23

• Organism :

  Human

• Source :

  E. coli

• Concentration :

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity :

  >95% as determined by SDS-PAGE

• Solubility :

  Reconstitute at 0.1mg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin.

• Function :

  Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells.

• Molecular Weight :

  13

• Shipping Conditions :

  Ambient Temperature

• Storage Conditions :

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance :

  Lyophilized Powder

• Formulation :

  Lyophilized from solution in 30mM Acetate buffer, pH 4

• CAS Number :

  9000-83-3