Recombinant Human GDF3

• Description:

  GDF-3 is a growth and differentiation factor which belongs to the TGF-beta superfamily. GDF-3 and GDF-9 are the only two members of the family which do not form disulfide-linked dimers. GDF-3 has been found in adult bone marrow, spleen, thymus, and adipose tissue. Although signaling in all other members of the family involve the BMP receptors ALK1,2,3, and 6, GDF-3 signals through BMP receptors ALK4 and 7.

• Gene Name:

  GDF3

• Gene Aliases:

  GDF-3
  Recombinant Human Growth Differentiation Factor 3 (GDF3)

• Gene ID:

  9573

• Accession Number:

  Q9NR23

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  Reconstitute at 0.1mg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin.

• Function:

  Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells.

• Molecular Weight:

  13

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from solution in 30mM Acetate buffer, pH 4

• CAS Number:

  9000-83-3