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Recombinant Human FGF6

CAT: 0171-Z101685Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0171-Z101685Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF-6 is a heparin binding protein of the FGF family which works to control cell division, differentiation, and function. These proteins are especially prominent during prenatal development and postnatal growth. It has been shown that FGF-6 functions as a mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells (N-linked glycosylation is required for the full mitogenic effect). It has also been shown that FGF-6 inhibits the terminal differentiation of myoblasts, cooperates with TGF-2-beta to promote chondrogenesis in embryonic somites, and is present in leukemia cell lines which may undergo platelet megakaryocytic differentiation.
CAS Number
9000-83-3
Gene Name
FGF6
Gene Aliases
FGF-6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6
Recombinant Human Fibroblast Growth Factor 6 (FGF6)
Gene ID
2251
Accession Number
P10767
Organism
Human
Source
E. coli
Concentration
< 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells
Molecular Weight
19
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2µm filtered solution in 10mM sodium phosphate and 50mM NaCl, pH 7.5

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