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Recombinant Human FGF21

CAT: 0171-Z101109Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0171-Z101109Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF-21 is a secreted growth factor of the FGF family, classified as an FGF-19 subfamily member. Proteins of the FGF family are known to play a central role with respect to both prenatal and postnatal growth and development, and regeneration of a variety of tissues by promoting cellular proliferation and differentiation. In the presence of beta Klotho (protein cofactor), FGF-21 signals via the FGFR receptors to stimulate insulin independent glucose uptake by adipocytes.
CAS Number
9000-83-3
Gene Name
FGF21
Gene Aliases
FGF-21
Recombinant Human Fibroblast Growth Factor 21 (FGF21)
Gene ID
26291
Accession Number
Q9NSA1
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The bioactivity was determined in a NIH/3T3 cell proliferation assay with an ED50 <1ng/ml.
Molecular Weight
19.7
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from 0.2 μm filtered solution in Tris and NaCl (pH 8.0)

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