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Recombinant Human FGF21

CAT: 0171-Z101105Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0171-Z101105Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF21 is a secreted growth factor of the FGF family, classified as an FGF19 subfamily member. Proteins of the FGF family are known to play a central role with respect to both prenatal and postnatal growth and development, and regeneration of a variety of tissues by promoting cellular proliferation and differentiation. In the presence of beta Klotho (protein cofactor), FGF21 signals via the FGFR receptors to stimulate insulin independent glucose uptake by adipocytes.
CAS Number
9000-83-3
Gene Name
FGF21
Gene Aliases
FGF-21
Recombinant Human Fibroblast Growth Factor 21 (FGF21)
Gene ID
26291
Accession Number
Q9NSA1
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The bioactivity was determined in a NIH/3T3 cell proliferation assay with an ED50 <1ng/ml.
Molecular Weight
19.7
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from 0.2 μm filtered solution in Tris and NaCl (pH 8.0)

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