Recombinant Human FGF19

• Description:

  Human FGF19 is expressed during brain development and embryogenesis and is a high-affinity, heparin-dependent ligand for FGF receptor 4. Among FGF family members, human FGF19 is most closely related to murine FGF15 and chicken FGF19. Recombinant Human FGF19 is a non-glycosylated, 21.9 kDa protein that contains 195 amino acid residues.

• Gene Name:

  FGF19

• Gene Aliases:

  Fibroblast Growth Factor-19, FGFJ

• Gene ID:

  9965

• Accession Number:

  O95750

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  The ED50 as determined by the dose-dependent stimulation of the proliferation of balb/c 3T3 cells is 100-150ng/ml

• Molecular Weight:

  21.9

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS

• CAS Number:

  9000-83-3