Recombinant Human FGF10

• Description :

  FGF-10 is involved in the initial budding as well as the continuous outgrowth of vertebrate limbs. FGF-10 mRNA is expressed preferentially in neurons but not in glial cells and may have a distinct role in the brain. Human FGF-10 is mitogenic for fetal rat keratinizing epidermal cells but not for NIH 3T3 cells. Recombinant FGF-10 induces the proliferation of human urothelial cells in vitro and induces the proliferation of transitional epithelium. FGF-10 is secreted by cultured mouse pre- adipocytes, prevention of FGF-10 signaling inhibits subsequent differentiation. The ability of embryonic fibroblasts derived from FGF-10 knock-out mice to differentiate into adipocytes is also impaired.

• Gene Name :

  FGF10

• Gene Aliases :

  FGF-10, FGFA, Keratinocyte growth factor-2
  Recombinant Human Fibroblast Growth Factor 10 (FGF10)

• Gene ID :

  2255

• Accession Number :

  O15520

• Organism :

  Human

• Source :

  E. coli

• Concentration :

  < 1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity :

  >95% as determined by SDS-PAGE

• Function :

  The bioactivity was determined in a NIH/3T3 cell proliferation assay. The ED50 was in the range of 0.05 - 0.5 ng/ml.

• Molecular Weight :

  19

• Shipping Conditions :

  Ambient Temperature

• Storage Conditions :

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance :

  Lyophilized Powder

• Formulation :

  Lyophilized from 0.2 μm filtered solution in PBS (pH 7.0) and 1mM DTT

• CAS Number :

  9000-83-3