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Recombinant Human EGFL7

CAT: 0171-Z101535Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0171-Z101535Size:25 µg
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Description
EGFL7 is an 31 kDa secreted protein that contains an Emilin-like (EMI) domain, and two epidermal growth factor (EGF) domains - one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble, similar to extracellular matrix (ECM) proteins and, thus, incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
CAS Number
9000-83-3
Gene Name
EGFL7
Gene Aliases
EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, MEGF7, EGF-L7, NOTCH4-like protein, Vascular endothelial statin, VE-statin, Zneu1
Recombinant Human Epidermal Growth Factor-Like Protein 7 (EGFL7)
Gene ID
51162
Accession Number
Q9UHF1
Organism
Human
Source
Insect cells
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The activity was determined by the ability to bind human NOTCH1 in functional ELISA.
Molecular Weight
31
Shipping Conditions
Ambient Temperature
Storage Conditions
This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant Human EGFL7 is lyophilized from a 0.2 μm filtered solution (pH 7.0) in 100 mM glycine, 10 mM NaCl, 10% glycerol and 5% trehalose.

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