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Recombinant Human DHH

CAT: 0171-Z101699Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z101699Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Desert Hedgehog protein is one of the three Hedgehog family proteins that is highly conserved and plays a role in many developmental processes in animals. DHH become biologically active following its autocatalytic cleavage. There is a high degree of residue homology between Sonic Hedgehog (SHH), Indian Hedgehog (IHH), and DHH. Despite their individual levels of expression and unique biological roles, the Hedgehog family members all use the same signalling pathway, and therefore, may be used interchangeably for some experimental purposes.
CAS Number
9000-83-3
Gene Name
DHH
Gene Aliases
Desert Hedgehog Protein, DHH
Recombinant Human Desert Hedgehog (DHH)
Gene ID
50846
Accession Number
O43323
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 500 μg/mL in sterile PBS
Function
Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 15­-45 µg/mL
Molecular Weight
20
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 0.2 mM DTT

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