Recombinant Human CXCL1

CAT: 0171-Z100287Size: 200 µgDry Ice: NoHazardous: No
CAT#:0171-Z100287Size:200 µg
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Description
A chemokine, the growth regulated oncogene-alpha is identical with MGSA (melanoma growth stimulatory activity) with its new designation being CXCL1. The expression of GRO can be induced by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.
CAS Number
9000-83-3
Gene Name
CXCL1
Gene Aliases
Growth Regulated Protein, Melanoma Growth Stimulatory Activity, GRO-alpha, MGSA-alpha, CXCL1, NAP-3, GRO1, C-X-C motif chemokine 1, GRO-alpha(1-73)
Recombinant Human Growth Regulated Alpha Protein (CXCL1)
Gene ID
2919
Accession Number
P09341
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Determined by the ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/mL
Molecular Weight
8
Shipping Conditions
Ambient Temperature
Storage Conditions
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favourable performance, avoid repeated handling and multiple freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in 40 mM NaCl and PB, pH 7.0

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