Recombinant Human Beta-NGF

• Description:

  β-NGF is a potent neurotrophic factor that plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. β-NGF belongs to the cysteine-knot family of growth factors that assume stable, disulfide-linked homodimeric structures. Recombinant human β-NGF shares approximately 90% homology with both the mouse and rat βNGF at the primary level.

• CAS Number:

  9000-83-3

• Gene Name:

  NGF

• Gene Aliases:

  β-NGF, Nerve Growth Factor

• Gene ID:

  4803

• Accession Number:

  P01138

• Organism:

  Human

• Source:

  E. coli

• Concentration:

  <1.0 EU/μg of recombinant protein as determined by the LAL method.

• Purity:

  >95% as determined by SDS-PAGE

• Solubility:

  A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

• Function:

  N.A.

• Molecular Weight:

  14

• Shipping Conditions:

  Ambient Temperature

• Storage Conditions:

  The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

• Appearance:

  Lyophilized Powder

• Formulation:

  Lyophilized from a 0.2µm filtered solution containing 0.1% TFA