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Recombinant Human AIMP1

CAT: 0171-Z100155Size: 20 µgDry Ice: NoHazardous: No
CAT#:0171-Z100155Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EMAP-II is activated during apoptosis by cleavage of pro-EMAP through caspase 8 and enhances the recruitment of inflammatory cells by its chemotactic properties. Besides its chemotactic effect on inflammatory cells, EMAP-II increases the adhesiveness of coronary artery smooth muscle cells (CASMC) for monocytes. EMAP-II also has anti-angiogenic properties, which are explained by its pro-apoptotic effect on endothelial cells.
CAS Number
9000-83-3
Gene Name
AIMP1
Gene Aliases
EMAP II, EMAP-2, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1, SCYE1
Recombinant Human Endothelial Monocyte-Activating Polypeptide 2 (AIMP1)
Gene ID
9255
Accession Number
Q12904
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
The ED(50) was determined by apoptotic effect on MCF-7 cells using a concentration of 10-50 ng/mL.
Molecular Weight
18
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered 20 mM PBS,130 mM NaCl solution pH 7.5

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