Kininogen Single Chain HMW from Plasma

• Description:

  Kininogen Single Chain HMW from Plasma_x000D_ Catalog number: B2016893_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 120 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Kininogen-1, High molecular weight kininogen (HMWK)_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Mori K, Nagasawa S. Studies on human high molecular weight (HMW) kininogen. II. Structural change of HMW kininogen by the action of human plasma kallikrein J Biochem. 1981 May;89(5):1465-73._x000D_ 2: Mori K, Sakamoto W, Nagasawa S. Studies on human high molecular weight (HMW) kininogen. III. Cleavage of HMW kininogen by the action of human salivary kallikrein J Biochem. 1981 Aug;90(2):503-9._x000D_ 3: Nakayasu T, Nagasawa S. Studies on human kininogens. I. Isolation, characterization, and cleavage by plasma kallikrein of high molecular weight (HMW)-kininogen J Biochem. 1979 Jan;85(1):249-58._x000D_ 4: Müller-Esterl W, Hock H, Rauth G, Kellermann J, Lottspeich F, Henschen A. Limited proteolysis of HMW kininogen by plasma kallikrein in man--evidence for a processing mechanism different from the bovine system Adv Exp Med Biol. 1986;198 Pt A:97-103._x000D_ 5: Higashiyama S, Ohkubo I, Ishiguro H, Kunimatsu M, Sawaki K, Sasaki M. Human high molecular weight kininogen as a thiol proteinase inhibitor: presence of the entire inhibition capacity in the native form of heavy chain Biochemistry. 1986 Apr 8;25(7):1669-75._x000D_ 6: Thompson RE, Mandle R Jr, Kaplan AP. Characterization of human high molecular weight kininogen. Procoagulant activity associated with the light chain of kinin-free high molecular weight kininogen J Exp Med. 1978 Feb 1;147(2):488-99._x000D_ 7: Kleniewski J, Donaldson VH. Comparison of human high molecular weight kininogen digestion by plasma kallikrein and by plasmin. A revised method of purification of high molecular weight kininogen J Lab Clin Med. 1987 Apr;109(4):469-79._x000D_ 8: Lämmle B, Zuraw BL, Heeb MJ, Schwarz HP, Berrettini M, Curd JG, Griffin JH. Detection and quantitation of cleaved and uncleaved high molecular weight kininogen in plasma by ligand blotting with radiolabeled plasma prekallikrein or factor XI Thromb Haemost. 1988 Apr 8;59(2):151-61._x000D_ 9: Muller-Esterl W, Dittmann B, Fritz H, Lottspeich F, Henschen A. Structural aspects of human kininogens Adv Exp Med Biol. 1983;156:157-64._x000D_ 10: Semba U, Umeda Y, Shibuya Y, Okabe H, Tanase S, Yamamoto T. Primary structures of guinea pig high- and low-molecular-weight kininogens Int Immunopharmacol. 2004 Oct;4(10-11):1391-400. _x000D_ _x000D_ Products Related to Kininogen Single Chain HMW from Plasma can be found at Biofluids

• Short Description:

  Catalog Number: B2016893 (1 mg)_x000D_ Kininogen Single Chain HMW from Plasma is a high quality protein found in human blood plasma that plays a role in the regulation of blood clotting and inflammation. It is a high molecular weight form of kininogen, which is involved in the production of bradykinin, a peptide that helps to dilate blood vessels and regulate blood pressure. This protein is important for maintaining normal physiological functions in the body. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5