Anti-Cytokeratin 7 (Glandular and Transitional Epithelial Marker) (KRT7/1499R), CF405S conjugate
CAT:
37-BNC041499-100
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Cytokeratin 7 (Glandular and Transitional Epithelial Marker) (KRT7/1499R), CF405S conjugate
- Description: This antibody recognizes an intermediate filament protein (IFP) of 55 kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7 ) from colon carcinomas (keratin 7-).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: CK-7, K2C7, Keratin 55K Type II Cytoskeletal, Keratin Simple Epithelial Type 1 K7, Keratin Type II Cytoskeletal 7, Krt2-7, KRT7, Sarcolectin, SCL, Type II Mesothelial Keratin K7, Type-II Keratin Kb7
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: KRT7
- Gene ID: 3855
- NCBI Gene ID: 411501
- UniProt: P08729
- Cellular Locus: Cytoskeleton
- Host: Rabbit
- Species Reactivity: Human
- Immunogen: Recombinant full-length human KRT7 protein
- Target Antigen: Cytokeratin 7
- Clonality: Recombinant Monoclonal
- Isotype: IgG κ
- Clone: KRT7/1499R
- Conjugation: CF405S
- Disease: Tumor
- Source: Animal
- Applications: Flow, intracellular (verified) | IHC, FFPE (verified) | WB (verified)
- Validated Applications: FC, IHC, FFPE, WB
- Field of Research: Cancer, Cytoskeleton
- Positive Control: HeLa cells. Carcinoma of ovary, lung, cervix, or breast
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 55 kDa
- Additionnal Information: Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min|Immunofluorescence 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years