Trimyristin--d15

Trimyristin--d15

• CAS Number: 1219804-94-0
• UNSPSC Description: Trimyristin--d15 is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].
• Target Antigen: Cholinesterase (ChE); Endogenous Metabolite; Isotope-Labeled Compounds; Phosphatase
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling;Others
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Solubility: 10 mM in DMSO
• Smiles: [2H]C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC(OC(COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)=O
• Molecular Weight: 738.25
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the NervousTissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported