Anti-TGF-beta (Transforming Growth Factor beta)(TGFB/510)

• Description:

  This MAb recognizes TGF beta 1, 2 and 3. TGFs inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.

• Synonyms:

  ARVD; BSC 1 cell growth inhibitor; CED; Cetermin; Diaphyseal dysplasia 1 (DPD1); Glioblastoma derived T cell suppressor factor (G TSF); Latency-associated peptide (LAP); Polyergin; Transforming growth factor beta 1 (TGF beta1 or TGFB1); TGF beta2 (TGFB2); TGF beta3 (TGFB3); TGFbeta (TGFB)

• CAS Number:

  9007-83-4

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  TFGB

• Gene ID:

  7040; 7042; 7043

• NCBI Gene ID:

  645227

• UniProt:

  P01137; P10600; P61812

• Cellular Locus:

  Secreted (extracellular)

• Host:

  Mouse

• Species Reactivity:

  Cow, Dog, Hamster, Human, Monkey, Mouse, Rat

• Immunogen:

  Full length recombinant human TGF-beta2 protein

• Target Antigen:

  TGF-Beta

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  TGFB/510

• Conjugation:

  Purified, BSA-free

• Source:

  Animal

• Field of Research:

  Signal transduction

• Positive Control:

  Ovarian carcinoma, lung tumor or skin. PC-3 cell line. Eahy926 cells.

• Concentration:

  1 mg/mL

• Buffer:

  PBS, no BSA, no azide

• Molecular Weight:

  ~13 kDa

• Additionnal Information:

  For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  -35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years