Recombinant AKT3 Protein

• Description:

  Recombinant AKT3 Protein_x000D_ Catalog number: B2017550_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 20 µg_x000D_ Molecular Weight or Concentration: 60.8 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: N/A_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Liu Q, Qu X, Xie X, He P, Huang S. Repression of Akt3 gene transcription by the tumor suppressor RIZ1 Sci Rep. 2018 Jan 24;8(1):1528._x000D_ 2: Mezzasalma TM, Kranz JK, Chan W, Struble GT, Schalk-Hihi C, Deckman IC, Springer BA, Todd MJ. Enhancing recombinant protein quality and yield by protein stability profiling J Biomol Screen. 2007 Apr;12(3):418-28._x000D_ 3: Zhu LP, Zhou JP, Zhang JX, Wang JY, Wang ZY, Pan M, Li LF, Li CC, Wang KK, Bai YP, Zhang GG. MiR-15b-5p Regulates Collateral Artery Formation by Targeting AKT3 (Protein Kinase B-3) Arterioscler Thromb Vasc Biol. 2017 May;37(5):957-968._x000D_ 4: Nakatani K, Sakaue H, Thompson DA, Weigel RJ, Roth RA. Identification of a human Akt3 (protein kinase B gamma) which contains the regulatory serine phosphorylation site Biochem Biophys Res Commun. 1999 Apr 21;257(3):906-10._x000D_ 5: Joy A, Kapoor M, Georges J, Butler L, Chang Y, Li C, Crouch A, Smirnov I, Nakada M, Hepler J, Marty M, Feuerstein BG. The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression J Neurooncol. 2016 Oct;130(1):43-52._x000D_ 6: Chen T, Li SJ, Chen B, Huang Q, Kong XY, Shen C, Gu HT, Wang XW. Akt3 is a target of miR-29c-3p and serves an important function in the pathogenesis of congenital heart disease Int J Mol Med. 2019 Feb;43(2):980-992._x000D_ 7: Alcantara D, Timms AE, Gripp K, Baker L, Park K, Collins S, Cheng C, Stewart F, Mehta SG, Saggar A, Sztriha L, Zombor M, Caluseriu O, Mesterman R, Van Allen MI, Jacquinet A, Ygberg S, Bernstein JA, Wenger AM, Guturu H, Bejerano G, Gomez-Ospina N, Lehman A, Alfei E, Pantaleoni C, Conti V, Guerrini R, Moog U, Graham JM Jr, Hevner R, Dobyns WB, O'Driscoll M, Mirzaa GM. Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly Brain. 2017 Oct 1;140(10):2610-2622._x000D_ 8: Quambusch L, Depta L, Landel I, Lubeck M, Kirschner T, Nabert J, Uhlenbrock N, Weisner J, Kostka M, Levy LM, Schultz-Fademrecht C, Glanemann F, Althoff K, Müller MP, Siveke JT, Rauh D. Cellular model system to dissect the isoform-selectivity of Akt inhibitors Nat Commun. 2021 Sep 6;12(1):5297._x000D_ 9: Peres J, Mowla S, Prince S. The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Oncotarget. 2015 Jan 30;6(3):1821-33._x000D_ 10: Shin I, Edl J, Biswas S, Lin PC, Mernaugh R, Arteaga CL. Proapoptotic activity of cell-permeable anti-Akt single-chain antibodies Cancer Res. 2005 Apr 1;65(7):2815-24. _x000D_ _x000D_ Products Related to Recombinant AKT3 Protein can be found at Proteins

• Short Description:

  Catalog Number: B2017550 (20 µg)_x000D_ Recombinant AKT3 protein is often used in research studies to investigate the function and regulation of AKT3 and its potential role in various diseases, such as cancer and diabetes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3