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Losulazine

CAT: 0804-HY-106447-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106447-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Losulazine is an antihypertensive agent acting by a sympatholytic mechanism. Losulazine's hypotensive activity depends on the presence of an intact, functional sympathetic nervous system[1].
CAS Number
72141-57-2
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/losulazine.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN(S(=O)(C2=CC=C(C=C2)F)=O)CC1)C3=CC=C(NC4=C5C=CC(C(F)(F)F)=CC5=NC=C4)C=C3
Molecular Formula
C27H22F4N4O3S
Molecular Weight
558.55
References & Citations
[1]G M Mesfin, et al. Mechanism of anestrus in rats treated with an antihypertensive agent, losulazine hydrochloride. Toxicol Appl Pharmacol. 1987 Jan;87 (1) :91-101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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