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(-) -Camphoric acid

CAT: 0804-HY-122808-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122808-01Size:100 mg
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Description
(-) -Camphoric acid is the less active enantiomer of Camphoric acid. Camphoric acid induces glutamate receptor expression. Camphoric acid also significantly induces the activation of NF-κB and AP-1. Camphoric acid significantly stimulates the differentiation of mouse osteoblastic MC3T3-E1 subclone 4 cells. Camphoric acid has weak regulatory function towards glutamate receptors. Camphoric acid can induce mRNA expression of glutamate signaling molecules and activate transcription factors, thereby stimulating osteoblast differentiation[1][2].
CAS Number
560-09-8
UNSPSC
12352211
Hazard Statement
H302
Target
AP-1; mGluR; NF-κB
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/minus-camphoric-acid.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C([C@]1(C)C(C)(C)[C@H](C(O)=O)CC1)O
Molecular Formula
C10H16O4
Molecular Weight
200.23
Precautions
H302
References & Citations
[1]Su-Ui Lee, et al. Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression. Amino Acids. 2010 Jan;38 (1) :85-93.|[2]Lee, S. U., et al., (2010) . Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression. Amino acids, 38 (1), 85–93.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported