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ISTH0036

CAT: 0804-HY-158821Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158821Size:1 Each
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Description
ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), can be use in the study of primary open angle glaucoma (POAG), and wet age-related macular degeneration.
CAS Number
2179222-27-4
UNSPSC
12352208
Target
TGF-beta/Smad
Type
Oligonucleotides
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/isth0036.html
Solubility
10 mM in H2O
Smiles
[IH6][SH4][3H].[HH].[HH].[HH].[HH].[HH].[HH].[HH].[HH].[HH].[HH].[HH].[HH].[HH]
References & Citations
[1]Pfeiffer N, Voykov B, Renieri G, et al. First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma filtration surgery. PLoS One. 2017;12 (11) :e0188899. Published 2017 Nov 30. doi:10.1371/journal.pone.0188899
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2

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