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AS1468240

CAT: 0804-HY-118803Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118803Size:1 Each
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Description
AS1468240 is an orally active inhibitor for anticoagulant factor Xa (fXa), that inhibits human fXa with IC50 of 8.7 nM. AS1468240 prolongs the coagulation time in mice[1].
CAS Number
365462-61-9
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/as1468240.html
Smiles
O=C(C1=CC(Cl)=CC(O)=C1NC(C2=CC=C(C=C2)N3CCN(CCC3)C)=O)NC4=NC=C(C=C4)Cl
Molecular Formula
C25H25Cl2N5O3
Molecular Weight
514.40
References & Citations
[1]Ishihara T, et al., Identification of potent orally active factor Xa inhibitors based on conjugation strategy and application of predictable fragment recommender system. Bioorg Med Chem. 2015 Jan 15;23 (2) :277-89.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19200857-01AS1468240

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