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SDC1 antibody

CAT: 0710-FNab10760Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10760Size:100 µg
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Background
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Synonyms
Syndecan-1 (SYND1) |SDC1|SDC
UniProt
P18827
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Syndecan 1
Target
SDC1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85-120 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P18827

Syndecan-1

SDC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P18827
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SDC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SYND1
EC number
—
Processing
Precursor
Secondary accessions
D6W523, Q53QV0, Q546D3, Q96HB7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

GlycoproteinHeparan sulfatePhosphoproteinProteoglycan

Cellular component

MembraneSecreted

Domain

SignalTransmembraneTransmembrane helix

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