Ceftezole

• Description :

  Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2].

• Product Name Alternative :

  CTZ

• UNSPSC :

  12352005

• Hazard Statement :

  H302+H312+H332-H410

• Target :

  Antibiotic; Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/ceftezole.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C(N12)=C(CSC3=NN=CS3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O

• Molecular Formula :

  C13H12N8O4S3

• Molecular Weight :

  440.48

• Precautions :

  P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P501

• References & Citations :

  [1]Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20 (3) :379-83.|[2]Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo) . 1976 Oct;29 (10) :1071-82.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β-lactam

• CAS Number :

  [26973-24-0]