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CCNE2 antibody

CAT: 0710-FNab10611Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10611Size:100 µg
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Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.
Synonyms
G1/S-specific cyclin-E2|CCNE2
Gene ID
9134
UniProt
O96020
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
G1/S-specific cyclin-E2
Target
CCNE2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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