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L 156373

CAT: 0804-HY-124391Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-124391Size:1 Each
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Description
L 156373 is a potent oxytocin receptor antagonist with Ki value of 150 nM[1][2].
CAS Number
122211-29-4
UNSPSC
12352005
Target
Oxytocin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/l-156373.html
Smiles
O=C1NC(CC2=CC=CC=C2)C(N(C(C(CC)C)C(N3NCCCC3C(N4NCCCC4C(N(C(CC5=CC=CC=C5)C(N6CCCC16)=O)C)=O)=O)=O)O)=O
Molecular Formula
C40H54N8O7
Molecular Weight
758.91
References & Citations
[1]Elbatrawi YM, et al. Total Synthesis of L-156,373 and an oxoPiz Analogue via a Submonomer Approach. Org Lett. 2018 May 4;20 (9) :2707-2710.|[2]Pettibone DJ, et al. A structurally unique, potent, and selective oxytocin antagonist derived from Streptomyces silvensis. Endocrinology. 1989 Jul;125 (1) :217-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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