Products for Research Use Only
RegisterLogin

Baohuoside I

CAT: 0804-HY-N0011-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0011-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.
CAS Number
113558-15-9
Product Name Alternative
Icariin-II; Icariside-II
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; CXCR
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Baohuoside-I.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : ≥ 32 mg/mL
Smiles
OC1=CC(O)=C2C(OC(C3=CC=C(OC)C=C3)=C(O[C@H](O[C@@H](C)[C@H](O)[C@H]4O)[C@@H]4O)C2=O)=C1C/C=C(C)\C
Molecular Formula
C27H30O10
Molecular Weight
514.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Kim B, et al. Baohuoside I suppresses invasion of cervical and breast cancer cells through the downregulation of CXCR4 chemokine receptor expression. Biochemistry. 2014 Dec 9;53 (48) :7562-9.|[2]Song J, et al. Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer. Chem Biol Interact. 2012 Jul 30;199 (1) :9-17.|[3]Wang L, et al. The flavonoid Baohuoside-I inhibits cell growth and downregulates survivin and cyclin D1 expression in esophageal carcinoma via β-catenin-dependent signaling. Oncol Rep. 2011 Nov;26 (5) :1149-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CXCR4

Related Products

CatalogName
HY-N2290Baohuoside VII
HY-N2280Baohuoside V
HY-E70040Endoglycoceramidase I (EGCase I)
HY-KE7028Not I
HY-KE8010Exonuclease I
HY-P11142Jelleine-I
HY-N5196Nocathiacin I
HY-N10917Xanthohumol I
HY-W442226PEG3-I
HY-19541-01I-CBP112

Alternative Products

CatalogName
N2538-20Baohuoside I
FB74456-01Baohuoside VII
AB1713Baohuoside V
MBS5758127Baohuoside II
C14115-01Baohuoside-VI

Popular Products