Products for Research Use Only
RegisterLogin

Lusvertikimab

CAT: 0804-HY-P99412-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P99412-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research[1].
CAS Number
2375835-91-7
Product Name Alternative
OSE-127
UNSPSC
12352203
Target
Interleukin Related
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lusvertikimab.html
Purity
99.41
Solubility
H2O
Smiles
[Lusvertikimab]
Molecular Weight
(145.64 kDa)
References & Citations
[1]Lennart Lenk, et al. The IL7R-Antagonist OSE-127 Blocks Acute Lymphoblastic Leukemia Development Via a Dual Mode of Action. ACUTE LYMPHOBLASTIC LEUKEMIAS: BIOMARKERS, MOLECULAR MARKERS AND MINIMAL RESIDUAL DISEASE IN DIAGNOSIS AND PROGNOSIS| NOVEMBER 15, 2022.|[2]Elodie Rivière, , et al. Interleukin-7/Interferon Axis Drives T Cell and Salivary Gland Epithelial Cell Interactions in Sjögren's Syndrome. Arthritis Rheumatol. 2021 Apr;73 (4) :631-640.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Isoform
IL-7

Alternative Products

CatalogName
MBS1563121-01Lusvertikimab
GTR18337882-01Lusvertikimab Antibody
MBS1563586-01Research Grade Lusvertikimab
E55B0800Lusvertikimab (Reference antibody)
ICH5183-200mgLusvertikimab Biosimilar - Research Grade
GTR18780684-01(Lusvertikimab) Biosimilar Reference Antibody
A138732Lusvertikimab Biosimilar (Monoclonal, IgG4)
21-929Lusvertikimab - Research Grade Biosimilar
GTR18697355-01Lusvertikimab Human Monoclonal Antibody
047665IL-7Ra/CD127 (lusvertikimab) discontinued

Popular Products